postnatal lethality, complete penetrance_Grhl1<tm1Jane>/Grhl1<tm1Jane>,Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre)8Brn/0

http://metadb.riken.jp/0011085I129S1SvC57BL6FVBNGrhl1tm1JaneGrhl1tm1JaneGrhl3tm1JaneGrhl3tm31JaneTgKRT14cre8Brn0Grhl3tm31JaneGrhl3tm1JaneTgKRT14cre8BrnGrhl1tm1Jane

postnatal lethality, complete penetrance_Grhl1<tm1Jane>/Grhl1<tm1Jane>,Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre)8Brn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• grainyhead-like 3 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655333
• grainyhead-like 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182540
• transgene insertion 8, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177242

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grhl1<tm1Jane>/Grhl1<tm1Jane>,Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre)8Brn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grhl3<tm3.1Jane>|Grhl3<tm1Jane>|Tg(KRT14-cre)8Brn|Grhl1<tm1Jane>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Michael. Cangkrama, et.al., Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life., The Journal of investigative dermatology, 2016, 136
  http://rdf.ncbi.nlm.nih.gov/pubmed/26975724