postnatal lethality, complete penetrance_Socs1<tm1Wehi>/Socs1<tm1Wehi>

http://metadb.riken.jp/0011085I129S1SvC57BL6Socs1tm1WehiSocs1tm1WehiSocs1tm1Wehi

postnatal lethality, complete penetrance_Socs1<tm1Wehi>/Socs1<tm1Wehi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• suppressor of cytokine signaling 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354910

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Socs1<tm1Wehi>/Socs1<tm1Wehi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Socs1<tm1Wehi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• J G. Zhang, et.al., The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11606785
• W S. Alexander, et.al., SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine., Cell, 1999, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/10490099
• R. Starr, et.al., Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1., Proceedings of the National Academy of Sciences of the United States of America, 1998, 95
  http://rdf.ncbi.nlm.nih.gov/pubmed/9826711