postnatal lethality, complete penetrance_Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Isl1<tm1(cre)Tmj>/Isl1<+>

http://metadb.riken.jp/0011085I129S2SvPas129X1SvJC57BL6DBA2Phox2btm3JbrPhox2btm3JbrIsl1tm1creTmjIsl1Isl1tm1creTmjIsl1Phox2btm3Jbr

postnatal lethality, complete penetrance_Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Isl1<tm1(cre)Tmj>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• paired-like homeobox 2b
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100882
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Isl1<tm1(cre)Tmj>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Isl1<tm1(cre)Tmj>|Isl1<+>|Phox2b<tm3Jbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Véronique. Dubreuil, et.al., Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19940179