postnatal lethality, complete penetrance_Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Egr2<tm2(cre)Pch>/Egr2<+>

http://metadb.riken.jp/0011085I129S2SvPasC57BL6DBA2Phox2btm3JbrPhox2btm3JbrEgr2tm2crePchEgr2Egr2Egr2tm2crePchPhox2btm3Jbr

postnatal lethality, complete penetrance_Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Egr2<tm2(cre)Pch>/Egr2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• early growth response 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95296
• paired-like homeobox 2b
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100882

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Phox2b<tm3Jbr>/Phox2b<tm3Jbr>,Egr2<tm2(cre)Pch>/Egr2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Egr2<+>|Egr2<tm2(cre)Pch>|Phox2b<tm3Jbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Véronique. Dubreuil, et.al., Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19940179