postnatal lethality, complete penetrance_Pdgfrb<tm14(Pdgfrb)Sor>/Pdgfrb<+>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0011085I129S4SvJaeSorC57BL6CBAPdgfrbtm14PdgfrbSorPdgfrbTgSox2cre1Amc0PdgfrbTgSox2cre1AmcPdgfrbtm14PdgfrbSor

postnatal lethality, complete penetrance_Pdgfrb<tm14(Pdgfrb)Sor>/Pdgfrb<+>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• platelet derived growth factor receptor, beta polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:97531
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdgfrb<tm14(Pdgfrb)Sor>/Pdgfrb<+>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdgfrb<+>|Tg(Sox2-cre)1Amc|Pdgfrb<tm14(Pdgfrb)Sor>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Lorin E. Olson, et.al., PDGFRβ signaling regulates mural cell plasticity and inhibits fat development., Developmental cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21664579