postnatal lethality, complete penetrance_Eif2ak3<tm1Dron>/Eif2ak3<tm1Dron>,Tg(GFAP-tTA)110Pop/0,Tg(tetO-Ifng)184Pop/0

http://metadb.riken.jp/0011085I129S6SvEvTacC57BL6DBA2SwissWebsterEif2ak3tm1DronEif2ak3tm1DronTgGFAPtTA110Pop0TgtetOIfng184Pop0TgGFAPtTA110PopEif2ak3tm1DronTgtetOIfng184Pop

postnatal lethality, complete penetrance_Eif2ak3<tm1Dron>/Eif2ak3<tm1Dron>,Tg(GFAP-tTA)110Pop/0,Tg(tetO-Ifng)184Pop/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 184, Brian Popko
  http://metadb.riken.jp/db/mgi_rdf/MGI:4355870
• eukaryotic translation initiation factor 2 alpha kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341830
• transgene insertion 110, Brian Popko
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702608

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eif2ak3<tm1Dron>/Eif2ak3<tm1Dron>,Tg(GFAP-tTA)110Pop/0,Tg(tetO-Ifng)184Pop/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(GFAP-tTA)110Pop|Eif2ak3<tm1Dron>|Tg(tetO-Ifng)184Pop

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * Swiss Webster

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Wensheng. Lin, et.al., Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma., The Journal of cell biology, 2005, 169
  http://rdf.ncbi.nlm.nih.gov/pubmed/15911877