postnatal lethality, complete penetrance_Hoxa4<tm1Bhr>/Hoxa4<tm1Bhr>,Hoxb4<tm1Bay>/Hoxb4<tm1Bay>

http://metadb.riken.jp/0011085I129S7SvEvBrdC57BL6Hoxa4tm1BhrHoxa4tm1BhrHoxb4tm1BayHoxb4tm1BayHoxa4tm1BhrHoxb4tm1Bay

postnatal lethality, complete penetrance_Hoxa4<tm1Bhr>/Hoxa4<tm1Bhr>,Hoxb4<tm1Bay>/Hoxb4<tm1Bay>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• homeobox B4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96185
• homeobox A4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96176

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hoxa4<tm1Bhr>/Hoxa4<tm1Bhr>,Hoxb4<tm1Bay>/Hoxb4<tm1Bay>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hoxa4<tm1Bhr>|Hoxb4<tm1Bay>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• G S. Horan, et.al., Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed., Genes & development, 1995, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7628700