postnatal lethality, complete penetrance_Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(Mef2c-cre)1Blk/0

http://metadb.riken.jp/0011085IC57BL6NTacCfl2tm1ItlCfl2tm1ItlTgMef2ccre1Blk0Cfl2tm1ItlTgMef2ccre1Blk

postnatal lethality, complete penetrance_Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(Mef2c-cre)1Blk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Brian L Black
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583678
• cofilin 2, muscle
  http://metadb.riken.jp/db/mgi_rdf/MGI:101763

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(Mef2c-cre)1Blk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cfl2<tm1Itl>|Tg(Mef2c-cre)1Blk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Pankaj B. Agrawal, et.al., Normal myofibrillar development followed by progressive sarcomeric disruption with actin accumulations in a mouse Cfl2 knockout demonstrates requirement of cofilin-2 for muscle maintenance., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22343409