postnatal lethality, incomplete penetrance_Braf<tm2.1Urr>/Braf<tm2.1Urr>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0011086I129C57BL6SJLBraftm21UrrBraftm21UrrTgNescre1Kln0TgNescre1KlnBraftm21Urr

postnatal lethality, incomplete penetrance_Braf<tm2.1Urr>/Braf<tm2.1Urr>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm2.1Urr>/Braf<tm2.1Urr>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Braf<tm2.1Urr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Verena. Pfeiffer, et.al., Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/23505473