postnatal lethality, incomplete penetrance_Braf<tm1Wds>/Braf<tm1Wds>,Raf1<tm2Bacc>/Raf1<+>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6SJLBraftm1WdsBraftm1WdsRaf1tm2BaccRaf1TgNescre1Kln0Braftm1WdsTgNescre1KlnRaf1Raf1tm2Bacc

postnatal lethality, incomplete penetrance_Braf<tm1Wds>/Braf<tm1Wds>,Raf1<tm2Bacc>/Raf1<+>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• v-raf-leukemia viral oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97847
• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Wds>/Braf<tm1Wds>,Raf1<tm2Bacc>/Raf1<+>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Braf<tm1Wds>|Tg(Nes-cre)1Kln|Raf1<+>|Raf1<tm2Bacc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Jian. Zhong, et.al., Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo., Nature neuroscience, 2007, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/17396120