postnatal lethality, incomplete penetrance_Slc18a2<tm1.1Bgir>/Slc18a2<tm1.1Bgir>,Slc6a4<tm1(cre)Xz>/Slc6a4<+>

http://metadb.riken.jp/0011086I129S1SvC57BL6JSlc18a2tm11BgirSlc18a2tm11BgirSlc6a4tm1creXzSlc6a4Slc6a4Slc6a4tm1creXzSlc18a2tm11Bgir

postnatal lethality, incomplete penetrance_Slc18a2<tm1.1Bgir>/Slc18a2<tm1.1Bgir>,Slc6a4<tm1(cre)Xz>/Slc6a4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:96285
• solute carrier family 18 (vesicular monoamine), member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:106677

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc18a2<tm1.1Bgir>/Slc18a2<tm1.1Bgir>,Slc6a4<tm1(cre)Xz>/Slc6a4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a4<+>|Slc6a4<tm1(cre)Xz>|Slc18a2<tm1.1Bgir>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Nicolas. Narboux-Nême, et.al., Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences., Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/21814181