postnatal lethality, incomplete penetrance_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Tfrc<tm3.1Nca>/Tfrc<tm3.1Nca>,Tg(Vil-cre)20Syr/0

http://metadb.riken.jp/0011086I129S4SvJaeC57BL6CD1DBA2GtROSA26Sortm1TfrcNcaGtROSA26SorTfrctm31NcaTfrctm31NcaTgVilcre20Syr0Tfrctm31NcaGtROSA26Sortm1TfrcNcaTgVilcre20SyrGtROSA26Sor

postnatal lethality, incomplete penetrance_Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Tfrc<tm3.1Nca>/Tfrc<tm3.1Nca>,Tg(Vil-cre)20Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transferrin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:98822
• transgene insertion 20, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053809
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Tfrc*)Nca>/Gt(ROSA)26Sor<+>,Tfrc<tm3.1Nca>/Tfrc<tm3.1Nca>,Tg(Vil-cre)20Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tfrc<tm3.1Nca>|Gt(ROSA)26Sor<tm1(Tfrc*)Nca>|Tg(Vil-cre)20Syr|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CD-1 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Alan C. Chen, et.al., Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/26324903