postnatal lethality, incomplete penetrance_E2f1<tm1Meg>/E2f1<tm1Meg>,Rb1<tm2.1Fad>/Rb1<tm2.1Fad>

http://metadb.riken.jp/0011086I129S4SvJaeC57BL6E2f1tm1MegE2f1tm1MegRb1tm21FadRb1tm21FadRb1tm21FadE2f1tm1Meg

postnatal lethality, incomplete penetrance_E2f1<tm1Meg>/E2f1<tm1Meg>,Rb1<tm2.1Fad>/Rb1<tm2.1Fad>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• E2F transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101941
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• E2f1<tm1Meg>/E2f1<tm1Meg>,Rb1<tm2.1Fad>/Rb1<tm2.1Fad>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rb1<tm2.1Fad>|E2f1<tm1Meg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Matthew J. Cecchini, et.al., A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice., Molecular and cellular biology, 2014, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/24662053