postnatal lethality, incomplete penetrance_Grhl3<tm1Bogi>/Grhl3<+>,Irf6<Gt(OST398253)Lex>/Irf6<+>

http://metadb.riken.jp/0011086I129S5SvEvBrdC57BL6C57BL6JGrhl3tm1BogiGrhl3Irf6GtOST398253LexIrf6Irf6GtOST398253LexIrf6Grhl3tm1BogiGrhl3

postnatal lethality, incomplete penetrance_Grhl3<tm1Bogi>/Grhl3<+>,Irf6<Gt(OST398253)Lex>/Irf6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• grainyhead-like 3 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655333
• interferon regulatory factor 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1859211

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grhl3<tm1Bogi>/Grhl3<+>,Irf6<Gt(OST398253)Lex>/Irf6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irf6<Gt(OST398253)Lex>|Irf6<+>|Grhl3<tm1Bogi>|Grhl3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Myriam. Peyrard-Janvid, et.al., Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development., American journal of human genetics, 2014, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/24360809