neonatal lethality, complete penetrance_Fgf8<tm1.2Mrt>/Fgf8<tm1.3Mrt>,Tg(Nes-cre)1Atp/0

http://metadb.riken.jp/0011087I129P2OlaHsdFVBNFgf8tm12MrtFgf8tm13MrtTgNescre1Atp0TgNescre1AtpFgf8tm13MrtFgf8tm12Mrt

neonatal lethality, complete penetrance_Fgf8<tm1.2Mrt>/Fgf8<tm1.3Mrt>,Tg(Nes-cre)1Atp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604
• transgene insertion 1, Andreas Trumpp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm1.2Mrt>/Fgf8<tm1.3Mrt>,Tg(Nes-cre)1Atp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Atp|Fgf8<tm1.3Mrt>|Fgf8<tm1.2Mrt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• A. Trumpp, et.al., Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch., Genes & development, 1999, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/10601039