neonatal lethality, complete penetrance_Atp1a3<Myk>/Atp1a3<Myk>

http://metadb.riken.jp/0011087I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3MykAtp1a3Myk

neonatal lethality, complete penetrance_Atp1a3<Myk>/Atp1a3<Myk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATPase, Na+/K+ transporting, alpha 3 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:88107

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atp1a3<Myk>/Atp1a3<Myk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atp1a3<Myk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/SvImJ * C57BL/6J * C57BL/6NCr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• Steven J. Clapcote, et.al., Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19666602