neonatal lethality, incomplete penetrance_Ptgs1<tm1Unc>/Ptgs1<tm1Unc>,Ptgs2<tm1Unc>/Ptgs2<tm1Unc>

http://metadb.riken.jp/0011088I129P2OlaHsdC57BL6JPtgs1tm1UncPtgs1tm1UncPtgs2tm1UncPtgs2tm1UncPtgs1tm1UncPtgs2tm1Unc

neonatal lethality, incomplete penetrance_Ptgs1<tm1Unc>/Ptgs1<tm1Unc>,Ptgs2<tm1Unc>/Ptgs2<tm1Unc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prostaglandin-endoperoxide synthase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97797
• prostaglandin-endoperoxide synthase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97798

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptgs1<tm1Unc>/Ptgs1<tm1Unc>,Ptgs2<tm1Unc>/Ptgs2<tm1Unc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptgs1<tm1Unc>|Ptgs2<tm1Unc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011088

文献

http://purl.org/net/cito/citesAsAuthority

• C D. Loftin, et.al., Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11158594