neonatal lethality, incomplete penetrance_Olig1<tm1(cre)Rth>/Olig1<tm1(cre)Rth>,Dlx1<tm1Rth>/Dlx1<tm1Rth>,Dlx2<tm1.1Rth>/Dlx2<tm1.1Rth>

http://metadb.riken.jp/0011088I129SSvEv129S4SvJaeC57BL6Olig1tm1creRthOlig1tm1creRthDlx1tm1RthDlx1tm1RthDlx2tm11RthDlx2tm11RthDlx2tm11RthDlx1tm1RthOlig1tm1creRth

neonatal lethality, incomplete penetrance_Olig1<tm1(cre)Rth>/Olig1<tm1(cre)Rth>,Dlx1<tm1Rth>/Dlx1<tm1Rth>,Dlx2<tm1.1Rth>/Dlx2<tm1.1Rth>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• distal-less homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:94901
• distal-less homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:94902
• oligodendrocyte transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355334

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Olig1<tm1(cre)Rth>/Olig1<tm1(cre)Rth>,Dlx1<tm1Rth>/Dlx1<tm1Rth>,Dlx2<tm1.1Rth>/Dlx2<tm1.1Rth>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dlx2<tm1.1Rth>|Dlx1<tm1Rth>|Olig1<tm1(cre)Rth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011088

文献

http://purl.org/net/cito/citesAsAuthority

• John C. Silbereis, et.al., Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain., Neuron, 2014, 81
  http://rdf.ncbi.nlm.nih.gov/pubmed/24507192