neonatal lethality, incomplete penetrance_Twist1<tm1Bhr>/Twist1<+>,Twist2<tm1(cre)Dor>/Twist2<+>

http://metadb.riken.jp/0011088I129Sv129X1SvJTwist1tm1BhrTwist1Twist2tm1creDorTwist2Twist2tm1creDorTwist2Twist1tm1BhrTwist1

neonatal lethality, incomplete penetrance_Twist1<tm1Bhr>/Twist1<+>,Twist2<tm1(cre)Dor>/Twist2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• twist basic helix-loop-helix transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98872
• twist basic helix-loop-helix transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Twist1<tm1Bhr>/Twist1<+>,Twist2<tm1(cre)Dor>/Twist2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Twist2<tm1(cre)Dor>|Twist2<+>|Twist1<tm1Bhr>|Twist1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011088

文献

http://purl.org/net/cito/citesAsAuthority

• Drazen. Šošić, et.al., Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity., Cell, 2003, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/12553906