neonatal lethality, incomplete penetrance_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>,Ppargc1b<tm1Dpk>/Ppargc1b<tm1Dpk>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0011088I129X1SvJFVBNPpargc1atm1DpkPpargc1atm1DpkPpargc1btm1DpkPpargc1btm1DpkTgMyh6cre2182Mds0Ppargc1atm1DpkTgMyh6cre2182MdsPpargc1btm1Dpk

neonatal lethality, incomplete penetrance_Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>,Ppargc1b<tm1Dpk>/Ppargc1b<tm1Dpk>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342774
• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• peroxisome proliferative activated receptor, gamma, coactivator 1 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444934

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ppargc1a<tm1Dpk>/Ppargc1a<tm1Dpk>,Ppargc1b<tm1Dpk>/Ppargc1b<tm1Dpk>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ppargc1a<tm1Dpk>|Tg(Myh6-cre)2182Mds|Ppargc1b<tm1Dpk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011088

文献

http://purl.org/net/cito/citesAsAuthority

• Ling. Lai, et.al., Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart., Genes & development, 2008, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/18628400