perinatal lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2.1Kem>,Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>/Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>,Tg(Cdx1-cre)23Kem/0

http://metadb.riken.jp/0011089I129S1Sv129S6SvEvTac129X1SvJC57BL6FVBCtnnb1tm2KemCtnnb1tm21KemGtROSA26Sortm1Ctnnb1KemGtROSA26Sortm1Ctnnb1KemTgCdx1cre23Kem0TgCdx1cre23KemCtnnb1tm2KemGtROSA26Sortm1Ctnnb1KemCtnnb1tm21Kem

perinatal lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2.1Kem>,Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>/Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>,Tg(Cdx1-cre)23Kem/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• transgene insertion 23, Rolf Kemler
  http://metadb.riken.jp/db/mgi_rdf/MGI:3841469
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm2Kem>/Ctnnb1<tm2.1Kem>,Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>/Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>,Tg(Cdx1-cre)23Kem/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cdx1-cre)23Kem|Ctnnb1<tm2Kem>|Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>|Ctnnb1<tm2.1Kem>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete perinatal lethality
  http://purl.obolibrary.org/obo/MP_0011089

文献

http://purl.org/net/cito/citesAsAuthority

• Stefan. Rudloff, et.al., Differential requirements for β-catenin during mouse development., Development (Cambridge, England), 2012, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/22991437