perinatal lethality, complete penetrance_Disp1<tm1Pab>/Disp1<tm1Pab>,Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0011089I129S1Sv129X1SvJC57BL6CBADisp1tm1PabDisp1tm1PabShhtm2ChgShhTgSox2cre1Amc0Shhtm2ChgDisp1tm1PabTgSox2cre1AmcShh

perinatal lethality, complete penetrance_Disp1<tm1Pab>/Disp1<tm1Pab>,Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dispatched RND transporter family member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916147
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537
• sonic hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:98297

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Disp1<tm1Pab>/Disp1<tm1Pab>,Shh<tm2Chg>/Shh<+>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shh<tm2Chg>|Disp1<tm1Pab>|Tg(Sox2-cre)1Amc|Shh<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete perinatal lethality
  http://purl.obolibrary.org/obo/MP_0011089

文献

http://purl.org/net/cito/citesAsAuthority

• Yina. Li, et.al., Cholesterol modification restricts the spread of Shh gradient in the limb bud., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16611729