perinatal lethality, complete penetrance_En1<tm1Alj>/En1<tm8.1Alj>,En2<tm1Alj>/En2<tm6Alj>,Gt(ROSA)26Sor<tm1(cre/ERT2)Alj>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0011089I129S2SvPas129S6SvEvTacSwissWebsterEn1tm1AljEn1tm81AljEn2tm1AljEn2tm6AljGtROSA26Sortm1creERT2AljGtROSA26SorGtROSA26Sortm1creERT2AljEn1tm1AljEn2tm1AljEn2tm6AljEn1tm81AljGtROSA26Sor

perinatal lethality, complete penetrance_En1<tm1Alj>/En1<tm8.1Alj>,En2<tm1Alj>/En2<tm6Alj>,Gt(ROSA)26Sor<tm1(cre/ERT2)Alj>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389
• engrailed 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95390

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm1Alj>/En1<tm8.1Alj>,En2<tm1Alj>/En2<tm6Alj>,Gt(ROSA)26Sor<tm1(cre/ERT2)Alj>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(cre/ERT2)Alj>|En1<tm1Alj>|En2<tm1Alj>|En2<tm6Alj>|En1<tm8.1Alj>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete perinatal lethality
  http://purl.obolibrary.org/obo/MP_0011089

文献

http://purl.org/net/cito/citesAsAuthority

• Yulan. Cheng, et.al., The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/20081196