perinatal lethality, complete penetrance_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0011089I129X1SvJC57BL6CBANotch1tm2RkoNotch1tm2RkoTgWnt1cre11Rth0TgWnt1cre11RthNotch1tm2Rko

perinatal lethality, complete penetrance_Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wnt1-cre)11Rth|Notch1<tm2Rko>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete perinatal lethality
  http://purl.obolibrary.org/obo/MP_0011089

文献

http://purl.org/net/cito/citesAsAuthority

• Ryan. Humphreys, et.al., Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22156581