prenatal lethality, complete penetrance_Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>/Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>,Tg(Sox2-cre)1Amc/?

http://metadb.riken.jp/0011091I129C57BL6CBAIgs1tm2CAGBgeoNdpEGFPNatIgs1tm2CAGBgeoNdpEGFPNatTgSox2cre1AmcIgs1tm2CAGBgeoNdpEGFPNatTgSox2cre1Amc

prenatal lethality, complete penetrance_Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>/Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>,Tg(Sox2-cre)1Amc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• intergenic site 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319510
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>/Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>,Tg(Sox2-cre)1Amc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igs1<tm2(CAG-Bgeo,-Ndp,-EGFP)Nat>|Tg(Sox2-cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Xin. Ye, et.al., Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization., Cell, 2009, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/19837032