prenatal lethality, complete penetrance_Pdha1<tm1Ptl>/Y,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0011091I129P2OlaHsdC57BL6FVBNSJLPdha1tm1PtlYTgNescre1Kln0TgNescre1KlnPdha1tm1Ptl

prenatal lethality, complete penetrance_Pdha1<tm1Ptl>/Y,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pyruvate dehydrogenase E1 alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97532
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdha1<tm1Ptl>/Y,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Pdha1<tm1Ptl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Lioudmila. Pliss, et.al., Biochemical and structural brain alterations in female mice with cerebral pyruvate dehydrogenase deficiency., Journal of neurochemistry, 2004, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/15569252