prenatal lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2.1Kem>,Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0011091I129S1Sv129S6SvEvTac129X1SvJC57BL6JCBAJCtnnb1tm2KemCtnnb1tm21KemGtROSA26Sortm1Ctnnb1KemGtROSA26SorTgWnt1cre11Rth0TgWnt1cre11RthGtROSA26Sortm1Ctnnb1KemCtnnb1tm2KemGtROSA26SorCtnnb1tm21Kem

prenatal lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2.1Kem>,Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm2Kem>/Ctnnb1<tm2.1Kem>,Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wnt1-cre)11Rth|Gt(ROSA)26Sor<tm1(Ctnnb1)Kem>|Ctnnb1<tm2Kem>|Gt(ROSA)26Sor<+>|Ctnnb1<tm2.1Kem>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Stefan. Rudloff, et.al., Differential requirements for β-catenin during mouse development., Development (Cambridge, England), 2012, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/22991437