prenatal lethality, complete penetrance_Casp8<tm1.1Yuan>/Casp8<tm1.1Yuan>

http://metadb.riken.jp/0011091I129S1Sv129X1SvJBALBcC57BL6MF1Casp8tm11YuanCasp8tm11YuanCasp8tm11Yuan

prenatal lethality, complete penetrance_Casp8<tm1.1Yuan>/Casp8<tm1.1Yuan>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261423

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp8<tm1.1Yuan>/Casp8<tm1.1Yuan>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp8<tm1.1Yuan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 * MF1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• E E. Varfolomeev, et.al., Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally., Immunity, 1998, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/9729047