prenatal lethality, complete penetrance_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Tie1-cre)9Ref/0

http://metadb.riken.jp/0011091I129S1Sv129X1SvJTgfbr2tm1KarlTgfbr2tm1KarlTgTie1cre9Ref0TgTie1cre9RefTgfbr2tm1Karl

prenatal lethality, complete penetrance_Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Tie1-cre)9Ref/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta receptor II
  http://metadb.riken.jp/db/mgi_rdf/MGI:98729
• transgene insertion 9, Reinhard Fassler
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388301

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>,Tg(Tie1-cre)9Ref/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tie1-cre)9Ref|Tgfbr2<tm1Karl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Rita L C. Carvalho, et.al., Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia., Development (Cambridge, England), 2004, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/15548578