prenatal lethality, complete penetrance_Nras<tm1Tyj>/Nras<+>,Meox2<tm1(cre)Sor>/Meox2<+>

http://metadb.riken.jp/0011091I129S4SvJaeSorC57BL6Nrastm1TyjNrasMeox2tm1creSorMeox2Meox2tm1creSorNrasNrastm1TyjMeox2

prenatal lethality, complete penetrance_Nras<tm1Tyj>/Nras<+>,Meox2<tm1(cre)Sor>/Meox2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neuroblastoma ras oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97376
• mesenchyme homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103219

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nras<tm1Tyj>/Nras<+>,Meox2<tm1(cre)Sor>/Meox2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Meox2<tm1(cre)Sor>|Nras<+>|Nras<tm1Tyj>|Meox2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Jinyong. Wang, et.al., Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner., Blood, 2011, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/21586752