prenatal lethality, complete penetrance_Ets1<tm1Jml>/Ets1<tm1Jml>,Ets2<tm5.1Rgo>/Ets2<tm5.1Rgo>,Meox2<tm1(cre)Sor>/Meox2<+>

http://metadb.riken.jp/0011091I129SSvEv129S4SvJaeSorC57BL6FVBNEts1tm1JmlEts1tm1JmlEts2tm51RgoEts2tm51RgoMeox2tm1creSorMeox2Ets2tm51RgoMeox2Ets1tm1JmlMeox2tm1creSor

prenatal lethality, complete penetrance_Ets1<tm1Jml>/Ets1<tm1Jml>,Ets2<tm5.1Rgo>/Ets2<tm5.1Rgo>,Meox2<tm1(cre)Sor>/Meox2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• E26 avian leukemia oncogene 2, 3' domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:95456
• mesenchyme homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103219
• E26 avian leukemia oncogene 1, 5' domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:95455

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ets1<tm1Jml>/Ets1<tm1Jml>,Ets2<tm5.1Rgo>/Ets2<tm5.1Rgo>,Meox2<tm1(cre)Sor>/Meox2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ets2<tm5.1Rgo>|Meox2<+>|Ets1<tm1Jml>|Meox2<tm1(cre)Sor>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Guo. Wei, et.al., Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis., Blood, 2009, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/19411629