embryonic lethality, complete penetrance_Gclc<tm1Dwn>/Gclc<tm1Dwn>

http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JGclctm1DwnGclctm1DwnGclctm1Dwn

embryonic lethality, complete penetrance_Gclc<tm1Dwn>/Gclc<tm1Dwn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate-cysteine ligase, catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:104990

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gclc<tm1Dwn>/Gclc<tm1Dwn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gclc<tm1Dwn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• T P. Dalton, et.al., Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous., Biochemical and biophysical research communications, 2000, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/11118286