embryonic lethality, complete penetrance_Trpm7<tm1Clph>/Trpm7<tm1.1Clph>,Tg(Sox2-cre)1Amc/0

http://metadb.riken.jp/0011092I129S4SvJaeC57BL6CBATrpm7tm1ClphTrpm7tm11ClphTgSox2cre1Amc0TgSox2cre1AmcTrpm7tm1ClphTrpm7tm11Clph

embryonic lethality, complete penetrance_Trpm7<tm1Clph>/Trpm7<tm1.1Clph>,Tg(Sox2-cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537
• transient receptor potential cation channel, subfamily M, member 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929996

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trpm7<tm1Clph>/Trpm7<tm1.1Clph>,Tg(Sox2-cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Sox2-cre)1Amc|Trpm7<tm1Clph>|Trpm7<tm1.1Clph>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Jie. Jin, et.al., Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis., Science (New York, N.Y.), 2008, 322
  http://rdf.ncbi.nlm.nih.gov/pubmed/18974357