embryonic lethality, complete penetrance_Cbfb<tm1Lhc>/Cbfb<+>,Tg(EIIa-cre)C5379Lmgd/0

http://metadb.riken.jp/0011092I129S6SvEvTacC57BL6FVBNCbfbtm1LhcCbfbTgEIIacreC5379Lmgd0TgEIIacreC5379LmgdCbfbCbfbtm1Lhc

embryonic lethality, complete penetrance_Cbfb<tm1Lhc>/Cbfb<+>,Tg(EIIa-cre)C5379Lmgd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion C5379, Laboratory of Mammalian Genes and Development, Heiner Westphal
  http://metadb.riken.jp/db/mgi_rdf/MGI:2137685
• core binding factor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:99851

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cbfb<tm1Lhc>/Cbfb<+>,Tg(EIIa-cre)C5379Lmgd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(EIIa-cre)C5379Lmgd|Cbfb<+>|Cbfb<tm1Lhc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Ya-Huei. Kuo, et.al., Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia., Cancer cell, 2006, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/16413472