embryonic lethality, complete penetrance_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Nes-cre)1Atp/0

http://metadb.riken.jp/0011092I129S6SvEvTacFVBNSmad4tm21CxdSmad4tm21CxdTgNescre1Atp0TgNescre1AtpSmad4tm21Cxd

embryonic lethality, complete penetrance_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Nes-cre)1Atp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andreas Trumpp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687337
• SMAD family member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:894293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Nes-cre)1Atp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Atp|Smad4<tm2.1Cxd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Yong-Xing. Zhou, et.al., Cerebellar deficits and hyperactivity in mice lacking Smad4., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12896967