embryonic lethality, complete penetrance_Dph1<tm2Bhr>/Dph1<+>,Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Mesp1<tm2(cre)Ysa>/Mesp1<+>

http://metadb.riken.jp/0011092I129SSvEv129S4SvJaeC57BL6JC57BL6NCrljCBAJNCrljDph1tm2BhrDph1GtROSA26Sortm1DTAJpmbGtROSA26SorMesp1tm2creYsaMesp1Mesp1GtROSA26SorDph1tm2BhrGtROSA26Sortm1DTAJpmbDph1Mesp1tm2creYsa

embryonic lethality, complete penetrance_Dph1<tm2Bhr>/Dph1<+>,Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Mesp1<tm2(cre)Ysa>/Mesp1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• diphthamide biosynthesis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151233
• mesoderm posterior 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107785

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dph1<tm2Bhr>/Dph1<+>,Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Mesp1<tm2(cre)Ysa>/Mesp1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mesp1<+>|Gt(ROSA)26Sor<+>|Dph1<tm2Bhr>|Gt(ROSA)26Sor<tm1(DTA)Jpmb>|Dph1<+>|Mesp1<tm2(cre)Ysa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Yi-Ru. Yu, et.al., Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome., Human molecular genetics, 2014, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/24895408