embryonic lethality, complete penetrance_Rock2<tm1.1Itl>/Rock2<tm1.1Itl>,Tg(Tagln-cre)1Her/0

http://metadb.riken.jp/0011092I129SSvEvC57BL6C57BL6JSJLRock2tm11ItlRock2tm11ItlTgTaglncre1Her0TgTaglncre1HerRock2tm11Itl

embryonic lethality, complete penetrance_Rock2<tm1.1Itl>/Rock2<tm1.1Itl>,Tg(Tagln-cre)1Her/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Joachim Herz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450259
• Rho-associated coiled-coil containing protein kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:107926

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rock2<tm1.1Itl>/Rock2<tm1.1Itl>,Tg(Tagln-cre)1Her/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tagln-cre)1Her|Rock2<tm1.1Itl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Toru. Shimizu, et.al., Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice., Arteriosclerosis, thrombosis, and vascular biology, 2013, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/24135024