embryonic lethality, complete penetrance_Bard1<tm1Thl>/Bard1<tm2Thl>,Tg(Hsp70-1-cre)1Arge/0

http://metadb.riken.jp/0011092I129Sv129S1SvC57BL6JCBABard1tm1ThlBard1tm2ThlTgHsp701cre1Arge0Bard1tm1ThlTgHsp701cre1ArgeBard1tm2Thl

embryonic lethality, complete penetrance_Bard1<tm1Thl>/Bard1<tm2Thl>,Tg(Hsp70-1-cre)1Arge/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• BRCA1 associated RING domain 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328361
• transgene insertion 1, Argiris Efstratiadis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447235

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bard1<tm1Thl>/Bard1<tm2Thl>,Tg(Hsp70-1-cre)1Arge/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bard1<tm1Thl>|Tg(Hsp70-1-cre)1Arge|Bard1<tm2Thl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S1/Sv * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Reena. Shakya, et.al., The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18443292