embryonic lethality, complete penetrance_Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>,Men1<tm1.1Ctre>/Men1<tm1.1Ctre>

http://metadb.riken.jp/0011092I129Sv129S6SvEvTacC57BL6Cdkn2ctm1YxiCdkn2ctm1YxiMen1tm11CtreMen1tm11CtreMen1tm11CtreCdkn2ctm1Yxi

embryonic lethality, complete penetrance_Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>,Men1<tm1.1Ctre>/Men1<tm1.1Ctre>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105388
• multiple endocrine neoplasia 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1316736

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>,Men1<tm1.1Ctre>/Men1<tm1.1Ctre>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Men1<tm1.1Ctre>|Cdkn2c<tm1Yxi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Xin-Hai. Pei, et.al., p18Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17409423