embryonic lethality, complete penetrance_Mark2<tm1Hpw>/Mark2<tm1Hpw>,Mark3<tm1Hpw>/Mark3<tm1Hpw>

http://metadb.riken.jp/0011092I129X1SvJC57BL6Mark2tm1HpwMark2tm1HpwMark3tm1HpwMark3tm1HpwMark2tm1HpwMark3tm1Hpw

embryonic lethality, complete penetrance_Mark2<tm1Hpw>/Mark2<tm1Hpw>,Mark3<tm1Hpw>/Mark3<tm1Hpw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MAP/microtubule affinity regulating kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:99638
• MAP/microtubule affinity regulating kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341865

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mark2<tm1Hpw>/Mark2<tm1Hpw>,Mark3<tm1Hpw>/Mark3<tm1Hpw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mark2<tm1Hpw>|Mark3<tm1Hpw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Jochen K. Lennerz, et.al., Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis., Molecular and cellular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20733003