embryonic lethality before implantation, complete penetrance_Rrm1<tm1.1Ofc>/Rrm1<tm1.1Ofc>,Tg(CAG-Rrm2)#Rsw/Tg(CAG-Rrm2)#Rsw

http://metadb.riken.jp/0011094I129C57BL6FVBNSJLRrm1tm11OfcRrm1tm11OfcTgCAGRrm2RswTgCAGRrm2RswRrm1tm11OfcTgCAGRrm2Rsw

embryonic lethality before implantation, complete penetrance_Rrm1<tm1.1Ofc>/Rrm1<tm1.1Ofc>,Tg(CAG-Rrm2)#Rsw/Tg(CAG-Rrm2)#Rsw

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Robert S Weiss
  http://metadb.riken.jp/db/mgi_rdf/MGI:5488613
• ribonucleotide reductase M1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98180

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rrm1<tm1.1Ofc>/Rrm1<tm1.1Ofc>,Tg(CAG-Rrm2)#Rsw/Tg(CAG-Rrm2)#Rsw

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rrm1<tm1.1Ofc>|Tg(CAG-Rrm2)#Rsw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality before implantation
  http://purl.obolibrary.org/obo/MP_0011094

文献

http://purl.org/net/cito/citesAsAuthority

• Julia. Specks, et.al., A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development., Molecular and cellular biology, 2015, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/26077802