embryonic lethality before implantation, complete penetrance_Topbp1<tm1.1Zqw>/Topbp1<tm1.1Zqw>

http://metadb.riken.jp/0011094I129P2OlaHsd129S4SvJaeSorTopbp1tm11ZqwTopbp1tm11ZqwTopbp1tm11Zqw

embryonic lethality before implantation, complete penetrance_Topbp1<tm1.1Zqw>/Topbp1<tm1.1Zqw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• topoisomerase (DNA) II binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920018

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Topbp1<tm1.1Zqw>/Topbp1<tm1.1Zqw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Topbp1<tm1.1Zqw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJaeSor

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality before implantation
  http://purl.obolibrary.org/obo/MP_0011094

文献

http://purl.org/net/cito/citesAsAuthority

• Zhong-Wei. Zhou, et.al., An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence., PLoS genetics, 2013, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/23950734