embryonic lethality between implantation and somite formation, complete penetrance_Frs2<tm3Scl>/Frs2<tm3Scl>

http://metadb.riken.jp/0011096EI129S6SvEvTacorI129S6SvEvTacSwissWebsterFrs2tm3SclFrs2tm3SclFrs2tm3Scl

embryonic lethality between implantation and somite formation, complete penetrance_Frs2<tm3Scl>/Frs2<tm3Scl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100860

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Frs2<tm3Scl>/Frs2<tm3Scl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Frs2<tm3Scl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Swiss Webster)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality between implantation and somite formation
  http://purl.obolibrary.org/obo/MP_0011096

文献

http://purl.org/net/cito/citesAsAuthority

• Y R. Hadari, et.al., Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11447289
• N. Gotoh, et.al., The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15870281