embryonic lethality between somite formation and embryo turning, complete penetrance_Mdm2<tm1Glo>/Mdm2<tm1Glo>,Trp53<tm1Adv>/Trp53<tm1Adv>

http://metadb.riken.jp/0011097I129S7SvEvBrdMdm2tm1GloMdm2tm1GloTrp53tm1AdvTrp53tm1AdvMdm2tm1GloTrp53tm1Adv

embryonic lethality between somite formation and embryo turning, complete penetrance_Mdm2<tm1Glo>/Mdm2<tm1Glo>,Trp53<tm1Adv>/Trp53<tm1Adv>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transformed mouse 3T3 cell double minute 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96952

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm2<tm1Glo>/Mdm2<tm1Glo>,Trp53<tm1Adv>/Trp53<tm1Adv>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mdm2<tm1Glo>|Trp53<tm1Adv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality between somite formation and embryo turning
  http://purl.obolibrary.org/obo/MP_0011097

文献

http://purl.org/net/cito/citesAsAuthority

• Tomoo. Iwakuma, et.al., Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice., Oncogene, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/15361844