embryonic lethality during organogenesis, complete penetrance_Inpp5b<tm1Nbm>/Inpp5b<tm1Nbm>,Ocrl<tm1Nbm>/Ocrl<tm1Nbm>

http://metadb.riken.jp/0011098EI129SSvEv129S6SvEvTacC57BL6orI129SSvEv129S6SvEvTacC57BL6NIHBlackSwissorI129SSvEv129S6SvEvTacNIHBlackSwissInpp5btm1NbmInpp5btm1NbmOcrltm1NbmOcrltm1NbmInpp5btm1NbmOcrltm1Nbm

embryonic lethality during organogenesis, complete penetrance_Inpp5b<tm1Nbm>/Inpp5b<tm1Nbm>,Ocrl<tm1Nbm>/Ocrl<tm1Nbm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• OCRL, inositol polyphosphate-5-phosphatase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109589
• inositol polyphosphate-5-phosphatase B
  http://metadb.riken.jp/db/mgi_rdf/MGI:103257

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Inpp5b<tm1Nbm>/Inpp5b<tm1Nbm>,Ocrl<tm1Nbm>/Ocrl<tm1Nbm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Inpp5b<tm1Nbm>|Ocrl<tm1Nbm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6) or (involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * NIH Black Swiss) or (involves: 129S/SvEv * 129S6/SvEvTac * NIH Black Swiss)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• P A. Jänne, et.al., Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice., The Journal of clinical investigation, 1998, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/9593760