embryonic lethality during organogenesis, complete penetrance_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

http://metadb.riken.jp/0011098I129129S7SvEvBrdC57BL6Dicer1tm1BdhDicer1tm1BdhNkx25tm1creRjsNkx25Dicer1tm1BdhNkx25tm1creRjsNkx25

embryonic lethality during organogenesis, complete penetrance_Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Bdh>/Dicer1<tm1Bdh>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dicer1<tm1Bdh>|Nkx2-5<tm1(cre)Rjs>|Nkx2-5<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Yong. Zhao, et.al., Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2., Cell, 2007, 129
  http://rdf.ncbi.nlm.nih.gov/pubmed/17397913