embryonic lethality during organogenesis, complete penetrance_Hand2<tm1Dsr>/Hand2<tm2.1Dsr>,Tg(Nkx2-5-cre)9Eno/0

http://metadb.riken.jp/0011098I129129S7SvEvBrdC57BL6Hand2tm1DsrHand2tm21DsrTgNkx25cre9Eno0TgNkx25cre9EnoHand2tm1DsrHand2tm21Dsr

embryonic lethality during organogenesis, complete penetrance_Hand2<tm1Dsr>/Hand2<tm2.1Dsr>,Tg(Nkx2-5-cre)9Eno/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 9, Eric N Olson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3514033
• heart and neural crest derivatives expressed 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103580

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hand2<tm1Dsr>/Hand2<tm2.1Dsr>,Tg(Nkx2-5-cre)9Eno/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nkx2-5-cre)9Eno|Hand2<tm1Dsr>|Hand2<tm2.1Dsr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Takatoshi. Tsuchihashi, et.al., Hand2 function in second heart field progenitors is essential for cardiogenesis., Developmental biology, 2011, 351
  http://rdf.ncbi.nlm.nih.gov/pubmed/21185281