embryonic lethality during organogenesis, complete penetrance_Braf<tm1Sva>/Braf<tm1.1Sva>,Raf1<tm1Bacc>/Raf1<tm2Bacc>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0011098I129P2OlaHsd129S1Sv129X1SvJC57BL6SJLBraftm1SvaBraftm11SvaRaf1tm1BaccRaf1tm2BaccTgNescre1Kln0Raf1tm2BaccTgNescre1KlnBraftm1SvaBraftm11SvaRaf1tm1Bacc

embryonic lethality during organogenesis, complete penetrance_Braf<tm1Sva>/Braf<tm1.1Sva>,Raf1<tm1Bacc>/Raf1<tm2Bacc>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• v-raf-leukemia viral oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97847
• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Sva>/Braf<tm1.1Sva>,Raf1<tm1Bacc>/Raf1<tm2Bacc>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Raf1<tm2Bacc>|Tg(Nes-cre)1Kln|Braf<tm1Sva>|Braf<tm1.1Sva>|Raf1<tm1Bacc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Jian. Zhong, et.al., Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo., Nature neuroscience, 2007, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/17396120