embryonic lethality during organogenesis, complete penetrance_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>,Rbx1<Gt(XB674)Byg>/Rbx1<Gt(XB674)Byg>

http://metadb.riken.jp/0011098I129P2OlaHsd129S4SvJaeSorC57BL6JCdkn1btm1MlfCdkn1btm1MlfRbx1GtXB674BygRbx1GtXB674BygCdkn1btm1MlfRbx1GtXB674Byg

embryonic lethality during organogenesis, complete penetrance_Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>,Rbx1<Gt(XB674)Byg>/Rbx1<Gt(XB674)Byg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ring-box 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891829
• cyclin-dependent kinase inhibitor 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:104565

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1b<tm1Mlf>/Cdkn1b<tm1Mlf>,Rbx1<Gt(XB674)Byg>/Rbx1<Gt(XB674)Byg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1b<tm1Mlf>|Rbx1<Gt(XB674)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Mingjia. Tan, et.al., RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19325126