embryonic lethality during organogenesis, complete penetrance_Pik3ca<tm3Bvan>/Pik3ca<tm3Bvan>,Tg(Tek-cre)1Ywa/0

http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6SJLPik3catm3BvanPik3catm3BvanTgTekcre1Ywa0TgTekcre1YwaPik3catm3Bvan

embryonic lethality during organogenesis, complete penetrance_Pik3ca<tm3Bvan>/Pik3ca<tm3Bvan>,Tg(Tek-cre)1Ywa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1206581
• transgene insertion 1, Masashi Yanagisawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450309

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3ca<tm3Bvan>/Pik3ca<tm3Bvan>,Tg(Tek-cre)1Ywa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tek-cre)1Ywa|Pik3ca<tm3Bvan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Mariona. Graupera, et.al., Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration., Nature, 2008, 453
  http://rdf.ncbi.nlm.nih.gov/pubmed/18449193